44P Prognostic value of androgen receptor expression in premenopausal women with estrogen receptor-positive breast cancer

The prognosis of breast cancer in pre-menopausal women is very variable and dependent on the interactions several biological factors. androgen receptor (AR) could be among prognostic variables related to survival although data scarce. aim study was examine relationship between expression outcomes estrogen (ER)-positive invasive carcinoma patients. We assessed AR ER-positive carcinomas correlated this pattern with clinical pathologic parameters: tumor size, lymph node status, progesterone (PgR) human epidermal growth factor type 2 (HER2) overexpression evaluated association these parameters using univariate analyses. Immunohistochemical analysis for AR, PgR, HER2 were carried out semiquantitative evaluation staining performed. demonstrated 61.44% No statistical difference relation age, PgR/HER2 status (p score = 0.758, 0.346, 0.604, 0.070, 0.48 respectively). not an independent progression free overall cancers. associated ER/PgR/HER2 status. Although has significance triple-negative cancer, it a marker hormone-positive premenopausal cancer.